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The only difference is CJC-1295's Drug Affinity Complex (DAC), a reactive linker that covalently binds serum albumin after injection and extends the half-life from minutes to 5.8-8.1 days

Neuropharmacology 66 , 202214 (2013)

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Based on contraindications documented in FDA-approved GLP-1 prescribing information, these medications are generally not appropriate for individuals with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2