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As you can see, low testosterone may cause body composition and weight changes that can lead to negative effects on insulin sensitivity and blood sugar levels

Gumuslu E, Mutlu O, Celikyurt IK, Ulak G, Akar F, Erden F, et al

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Importantly, this pathway is enzymatically tractable, as the enzymes that control CoQ 10 reduction are druggable oxidoreductases, making the CoQ 10 axis a promising pharmacological entry point for ferroptosis-based cancer therapy