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The concentrations of the various macrospecies comprise the sum of the concentration of those microspecies that contain the same number of protons, for example in GSH: Determination of the redox potential of the GSSG/GSH system was achieved indirectly, applying a redox couple with a known standard redox potential

In doing so, glutathione ensures that the skin is protected against problems like wrinkles, blemishes, and discolorations

This biosynthetic process is mediated by glutamate-cysteine ligase (GCL), which includes glutamate-cysteine ligase catalytic subunit(GCLC) and GSH synthetase(GSS) [8]