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This enhanced delivery is particularly important given that glutathione levels naturally decline with age and are rapidly depleted during periods of increased oxidative stress [3]

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Specifically, the physicochemical and biological mechanisms through which nanoencapsulation enhances the stability, solubility, bioavailability, and targeted delivery of bioactive compounds (shown in Figure 2) are explored, as understanding these mechanisms is essential for translating engineering innovations into effective, evidence-based nutritional interventions

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