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Numerous studies have confirmed that effective management of these risk factors can significantly improve disease symptoms and reduce the recurrence and rehospitalization rates of CVD, thereby extending patient life expectancy and improving quality of life

[1] This is more conservative than the label's per-escalation-step language, but given the stakes of unintended pregnancy on a teratogen-risk medication, the additional conservatism is warranted

The Bridge criteria look like a deliberate map of cardiovascular and metabolic risk

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