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l3 In the liver, distribution of GSH is heterogeneous, which may play a significant role in susceptibility to acute hepatotoxicity from various toxic compounds such as acetaminophen metabolites, redox cycling compounds, peroxides, and others
It belongs to a class of drugs known as GLP-1 receptor agonists, which help regulate blood sugar levels and reduce appetite
doi:10.1002/mc.20741, PMID: 21319226 Yue P, Zhou Z, Khuri FR, Sun SY (2006) Depletion of intracellular glutathione contributes to JNK-mediated death receptor 5 upregulation and apoptosis induction by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate (CDDO-Me)
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