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Because GLP-1 drugs like semaglutide and exenatide contain complex peptide structures and are sensitive to degradation pathways such as oxidation and deamidation, robust MS characterization is essential throughout development, manufacturing, and stability studies

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We acknowledge that our inclusion of heart failure patients irrespective of their left ventiruclar ejection fraction (LVEF) is a limitation, as LVEF may not always be reported consistently across studies