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Conclusion In this large real-world study emulating a target trial, initiation of GLP-1 RA therapy among patients with T2DM was associated with a modestly higher incidence of psoriasis and lower incidences of pemphigus and bullous pemphigoid compared with DPP-4i therapy, while no increased risk was observed for most other autoimmune or inflammatory skin diseases

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Examples of steroid medications include prednisone, cortisone, hydrocortisone, and methylprednisolone

Bob Siegel, director of the Center for Better Health and Nutrition at Cincinnati Childrens Hospital, favors starting with intensive lifestyle changes in diet and exercise, given the lifetime ahead for 6-year-olds and the limited knowledge about long-term medication use