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For fatty liver disease itself , NICE guideline NG49 recommends risk stratification in primary care using the FIB-4 score initially, followed by the Enhanced Liver Fibrosis (ELF) test if indicated, to identify patients at higher risk of advanced fibrosis who may require specialist referral

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Nrf2 knockdown prevents NFT-dependent increase in cellular glutathione levels To examine the correlation between Nrf2 activation and the increase in glutathione levels after NFT treatment, Nrf2 protein levels were experimentally lowered by siRNA-mediated knockdown, which was confirmed by Western blotting (Fig