retatrutide effect on heart rate

retatrutide effect on heart rate side effects: what the trials show and how to manage them Retatrutide as a Novel Treatment

Name: retatrutide effect on heart rate side effects: what the trials show and how to manage them Retatrutide as a Novel Treatment
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Description

The STEP 1 trial (Wilding et al., The Lancet, 2021) showed an average weight loss of 14.9% over 68 weeks versus 2.4% in the placebo group a landmark result that established semaglutide as the benchmark for GLP-1 weight loss

It is still an investigational drug undergoing Phase 3 clinical trials

Parkman HP, Yates KP, Hasler WL, et al

The rationale for this approach was to investigate if GLP-1 signalling could cause metabolic reprograming that would persist after removal of receptor stimulation (Fig