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"So it's very challenging," Yacawych says, "to be able to separate these side effects, like nausea, from GLP-1's intended effects, like weight loss." A possible workaround came from a team led by Ernie Blevins of the University of Washington

The post describes microdose protocols as using lower starting doses with gradual increases, which may let the gastrointestinal system adapt with fewer acute side effects, but it also notes that this approach extends the time needed to reach a therapeutic effect

While reflexology (once called Zone Therapy) is arguably thousands of years old, its modern use was made popular by an ear-nose-throat specialist who used the pressure from rubber bands applied to the fingers and toes for surgical anesthesia

Ro, founded as Roman in 2017, is part of a growing crop of digital health companies aiming to capitalize on the soaring demand for GLP-1s by building programs and services for users on top of the medications