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Effect of leptin replacement on brain structure in genetically leptin-deficient adults

Thomas Karagiannis and his team from Aristotle University of Thessaloniki, Greece, amalgamated data from 22 independent studies

In a casecontrol design, patients electing to receive GLP-1-RA therapy in addition to UCWM were included based on the following inclusion criteria: definite IIH according to the modified Friedman criteria [17], BMI $\ge$ 30 kg/m 2 , and a follow-up of $\ge$ 6 months