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This finding is consistent with the lack of concurrent changes in the biochemical bone metabolism parameters in the study participants

Lifestyle choices also matter

In many cases, optimising nutritional status and addressing the underlying cause is as important as the isolated blood carnitine concentration

SURMOUNT-5 Trial Results This Phase 3b, open-label trial randomized 751 adults with obesity (but without diabetes) to receive either: Maximum tolerated dose of tirzepatide (10 mg or 15 mg) Maximum tolerated dose of semaglutide (1.7 mg or 2.4 mg) Key findings at 72 weeks: The trial concluded that tirzepatide was superior to semaglutide with respect to reduction in body weight and waist circumference at week 72