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At high oral doses, vitamin C absorption is significantly limited

Continued research will likely uncover further applications and refine the understanding of its mechanisms and efficacy, offering more precise guidelines for its use in medicine and skin care

The therapeutic efficacy of Mel-HA-MN was evaluated using the rat adjuvant-induced arthritis (AIA) model, where the microneedles penetration ability was tested by applying the patch on the rats abdominal skin ( Results demonstrated that Mel-HA-MN effectively penetrated the skin to a depth of approximately 200 m

* P -values are derived from generalized mixed effect models