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Creatine alleviates doxorubicin-induced liver aamage by inhibiting liver fibrosis, inflammation, oxidative stress, and cellular senescence

Some drugs having a catechol structure, used in the treatment of hypertension, asthma and Parkinson's disease, can be also O-methylated by the COMT, thus preventing the formation of toxic quinones (Vereczkey et al., 1998