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Before starting tirzepatide, it is important to inform your care team if you have any of the following conditions: endocrine tumors, eye disease, gallbladder disease, pancreatitis, kidney disease, stomach or intestine problems, or a history of thyroid cancer

Most large studies are funded by large pharmaceutical companies, and there is no incentive for them to continue research of drugs once they are off-patent

These receptors help regulate appetite and feelings of fullness, which can lead to reduced hunger and decreased food intake

Clinical studies have shown substantial weight loss with retatrutide, particularly at higher doses over longer treatment periods