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(1981) confirmed significant acute and delayed effects on human sleep behavior

Available at: Guidance for opioid reduction in primary careJQ/HW clinical leads (Cited April 15, 2023)

If you think you would benefit from MAT, call your doctor

In addition, for neuropathic pain in advanced cancer patients with opioid failure, the combination with an adjuvant effective in neuropathic cancer pain (GABA-inhibitors, duloxetine, tricyclic antidepressants) has to be considered (5)