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Expectations of Semaglutide Treatment Initiating semaglutide treatment typically involves starting at the lowest dosage, then incrementally adjusting based on individual response and tolerance to ensure an optimal balance for weight reduction

| Milestone | Ozempic (Semaglutide) | Trulicity (Dulaglutide) | |---|---|---| | Starting dose | 0.25 mg/week | 0.75 mg/week | | First escalation | 0.5 mg at week 4 | 1.5 mg at week 4 | | Second escalation | 1.0 mg at week 8 | 3.0 mg at week 24 | | Maximum approved dose (T2D) | 2.0 mg/week | 4.5 mg/week | | Minimum effective dose | 0.5 mg/week | 0.75 mg/week | Semaglutide reaches its minimum effective dose faster

Its a competitive market (fighting against giants like AbbVies Humira/Skyrizi), but Taltz has carved out a very profitable niche