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Facial fat compartments beyond the submental area, for example, present a greater risk of nerve injury, while areas such as the ankles should not be treated because the apparent fullness is often related to underlying anatomical structures rather than excess fat

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Parents pass this tendency to kids, who may pass it on

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Phase 2 trials showed 17.5% weight loss at 24 weeks and 24.2% at 48 weeks at the 12mg dose

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Trial registration UMIN000011118 (date of registration: July 4, 2013)

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