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More often than not, patients may need to try lower doses of the medication or an alternative class of GLP-1 agonists, as there is a variation in tolerability profile between them, says Criner

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More frequent checking is generally not needed since A1C reflects a three-month average, so checking more often than every three months provides limited additional information

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Patients taking tirzepatide reached a mean maximum reduction of 14.7% of body weight, or 16.0 kilograms, compared with 10.8%, or 11.6 kilograms, for semaglutide

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