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Additionally, some skeptics argue that certain naturopathic treatments lack scientific plausibility or are based on pseudoscientific principles

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Patients should be educated about red flag symptoms requiring urgent medical review, including: Severe, persistent abdominal pain (possible pancreatitis) Right upper quadrant pain, fever, or jaundice (possible gallbladder disease) Signs of dehydration (dizziness, reduced urine output, dry mouth) Symptoms of hypersensitivity (rash, swelling, breathing difficulties) Unexplained neck swelling or hoarseness (thyroid concerns) Severe hypoglycaemia (confusion, loss of consciousness) New or worsening visual symptoms Regular follow-up with the prescribing clinician, typically a GP or specialist diabetes team, ensures that any concerns are addressed promptly and that treatment remains appropriate for the individual patient's needs

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Iron deficiency-induce Fe-S synthesis disorders affect the voltage-dependent anion channel in the mitochondrial membrane, interferes with the overall stability of mitochondria, and induces apoptosis [292]

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