glutathione medscape system enhancement for cardiac protection: pharmacological options against oxidative stress and ferroptosis Glutathione | Synthesis Peptides

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Health 50 , 329340 (1982)

GHK-Cu also enhances the production of specialized pro-resolving mediators (SPMs), including resolvins and protectins, which actively promote the clearance of inflammatory debris and the restoration of tissue homeostasis

This is the theoretical basis for endogenously supplied gamma-glutamylcysteines ability to raise GSH levels, as being the product of the GCL enzyme, it can be taken up by cells intact, where it feeds directly into glutathione synthase to be converted to glutathione, effectively bypassing the dysfunctional GCL