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People with cirrhosis or significant liver dysfunction should avoid supplements without hepatologist guidance

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Serious Side Effects Rare but serious risks may include: Severe pancreatitis (persistent severe abdominal pain) Gallbladder problems Severe dehydration Kidney injury Allergic reactions Possible thyroid tumors (based on animal studies) Seek immediate medical attention if there is: Severe, ongoing abdominal pain Swelling of the face or throat Difficulty breathing Signs of severe dehydration Drug Interactions Semaglutide may interact with other medications