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Surface & Footwear Avoid prolonged training on concrete or other unforgiving surfaces.60 Wear sport-specific shoes with appropriate cushioning and support

HUBERMAN: So again, you want to avoid food in the hour and a half, probably two hours before taking them, and certainly in the half hour or longer after, which is why most people take them right before going to sleep, and add or augment that big growth hormone pulse that occurs in the early part of the night

Modulation of transforming growth factor-beta (TGF-beta), integrins, and stem cell pathways have also been observed

although higher doses can be split into multiple sites if needed