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En los casos en los que se deba sustituir el tratamiento con un anlogo de GLP-1 por una de estas alternativas, se deben tener en cuenta las siguientes consideraciones: Se debe comenzar a administrar el nuevo tratamiento una semana despus de la ltima dosis de Ozempic/Trulicity

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A recurring theme across non-incretin metabolic peptides is that early development efforts were constrained by pleiotropy, cardiovascular effects, or incomplete receptor characterization rather than by lack of metabolic relevance