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Common Side Effects (Generally Mild): Temporary injection site reactions (redness, slight swelling) Mild fatigue initially (as metabolism adjusts) Occasional flushing or warmth Slight changes in appetite Contraindications and Precautions: Pregnancy or breastfeeding (insufficient safety data) Active cancer (theoretical concerns about growth pathways) Severe kidney or liver disease (requires monitoring) Hypoglycemia risk (monitor if on diabetes medications) Medical Monitoring: At The Lamkin Clinic, we monitor MOTS-C patients with: Baseline metabolic labs (glucose, HbA1c, insulin, lipids) Follow-up testing at 8-12 weeks Body composition analysis Assessment of symptoms and energy levels Adjustment of other medications as metabolism improves Important: MOTS-C should only be used under the guidance of a qualified healthcare provider experienced in peptide therapy

Psoriasis (Auckl) 14:143152 Takeshita J et al (2017) Psoriasis and comorbid diseases: epidemiology

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It has been designated an orphan drug for a variety of conditions