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2007 Dec;100(2):513-24

The secret is to take small, frequent sips of water throughout the day

That is how they reduce appetite

How GLP-1 Medications Work for Weight Loss These treatments can help people lose weight because they: Reduce appetite Slow digestion Help you feel satisfied after smaller meals Support blood sugar control Reduce cravings or make them easier to manage The UK's Medicines and Healthcare products Regulatory Agency (MHRA) recognises Saxenda, Mounjaro, and Wegovy injection as licensed GLP-1 receptor agonists (RA) for weight management in people with obesity or overweight with a weight related health condition in the UK