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Meanwhile, the traditional managers of drug benefits, like pharmacy benefit management companies, are under fire for a lack of transparency in how they make money, with many of them eliminating controversial rebates they are paid by drug makers or working to scale them back to give their clients a bigger discount on prescription drugs

In addition to the drug or placebo injection, participants received individual counselling sessions every 4 weeks to help them adhere to a reduced-calorie diet (500 calories deficit per day relative to their own starting calorie intake) and increased physical activity (150 minutes a week)

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The reduced appetite often means you stop eating earlier in the evening, which itself has metabolic benefits for blood sugar and sleep quality