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Commenting on the study for Science Media Centre, Professor of Cancer Epidemiology Paul Pharoah said, While these results suggest that GLP1 receptor agonist have an effect on cancer risk the presence of an association does not mean that the association is a causal one. An observational study, no matter how carefully conducted, cannot replicate a randomised controlled trial, which would be regarded as gold standard to evaluate the effects of a drug. Inflammation We said some of the documented effects of GLP-1RAs were surprising, and that pretty much all bodily systems could be fair game

For heme iron (around 25% of the total), hydrolysis from hemoglobin/myoglobin is a crucial step before absorption, involving digestion in the gastric and small intestine by proteases

Acid Stability Sikiric et al

Microbiome uncertainty: While bacterial shifts may be helpful, the long-term effects arent fully known and may contribute to bloating or unpredictable bowel habits