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Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

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The brains were homogenized using a homogenizer and then diluted in 0.1 M phosphate buffer with a pH of 7.0 maintaining a 1:10 weight-to-volume ratio

It is referenced in scientific literature for its role in cellular signaling research, angiogenic pathway studies, and peptide interaction with nitric oxiderelated mechanisms