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placebo in 25 patients with BD, positive results were seen with significant reductions of the severity of mania within 6 h in the verum group, whose activity may be explained by competitive inhibition of phenylalanine and tyrosine, which are necessary for dopamine synthesis (288)

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PMID 8521505

In the periphery, GLP-1 is released from the gut in response to the presence of food nutrients