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Given that glutathiones primary function is to neutralize these free radicals, excessive coffee consumption might counteract the antioxidant benefits of glutathione

If any program tries to tell you otherwise, it is snake oil

LeidyHJCliftonPMAstrupAWycherleyTPWesterterp-PlantengaMSLuscombe-MarshNDet al

This discovery might have implications also for SnCE2-5 for which no enzymatic activity could be identified so far maybe exerting a dominant negative effect 26