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Tight Junction (TJ) proteins, located in the apical part of the intestinal epithelial cells, are crucial elements to ensure the functionality and integrity of the mucosal barrier (Ulluwishewa et al., 2011

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Research goals: Longevity & Anti-Aging, Metabolic & Weight Description 5-Amino-1MQ (5-amino-1-methylquinolinium iodide) is a small-molecule, membrane-permeable inhibitor of nicotinamide N-methyltransferase (NNMT), the enzyme that converts nicotinamide and S-adenosyl-l-methionine (SAM) into 1-methylnicotinamide and S-adenosyl-l-homocysteine