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353 Collectively, these genetic disorders underscore the non-redundant role of the UPS in preventing protein aggregation and preserving neuronal viability

With inhalation, the ribcage expands as the ribs move upward and outward

This requires that the microenvironment be composed in part by basic amino acids in proximity to the cysteine to allow dissociation of the thiol, which normally has a pK a of around 8.3

These findings highlight the role of astrocytes in maintaining redox balance in the brain not only through direct antioxidant mechanisms but also through intercellular metabolic support