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297,298 Additionally, two other key trials of SGLT-is in people with CKD showed that canagliflozin reduced the primary composite outcome of ESRD (dialysis, transplantation, or a sustained estimated eGFR 45 ml/min/1.73m 2 and a urinary-to-creatinine ratio (uACR) 25 mg/mmol or 2045 ml/min/1.73 m 2 or established CVD are recommended for diabetic patients because of its high glucose-lowering efficacy and proven cardiorenal benefits

Both results wiped significant value from Novo's share price as investors' hopes of finding a superior alternative to the company's existing Wegovy injection and rival Eli Lily's Zepbound, both GLP-1 medications, were dashed

Kisspeptin treatment induces gonadotropic responses and rescues ovulation in a subset of preclinical models and women with polycystic ovary syndrome

What happens when consumers stop taking their GLP-1 medications? Circana said