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For example, individuals with Lebers disease, a rare genetic disorder, may be at risk of optic nerve damage from B12 injections

PMID 26288227

K-means clustering was performed on the genera relative abundance data using the R script in the Supplementary Materials Scripts .zip file (KMScript), and clusters were plotted

it is an evolving aspirational treatment goal 14,15 normalisation of inflammatory markers (C-reactive protein [CRP] and faecal calprotectin) these noninvasive disease activity markers have been shown to correlate with endoscopic activity in UC and have an established role as surrogate indices 16 normal health-related quality of life improvement in quality of life may require additional measures, such as dietary and psychological therapies, as well as independent management of immune-mediated extraintestinal manifestations