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It may lose potency unpredictably
No organ toxicity, no carcinogenicity signals, no reproductive toxicity have been demonstrated in animal models to date
Altered antioxidant capacity in human renal cell carcinoma: role of glutathione-associated enzymes
Meanwhile, fecal microbiology combined with 16S rDNA analysis showed that Jiawei Xiaoyao Powder [consisting of Chinese herbs such as Radix Angelicae Sinensis, Radix Bupleurum, Radix Codonopsis Pilosulae, Radix Paeoniae Alba and Radix Paeoniae Lactiflora] significantly altered the composition of gut microbiota and affected the biosynthesis of 11 differential metabolites, such as primary bile acids and interferon-, in liver cancer rats, thus achieving the goal of adjuvant therapy for liver cancer (51)
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