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Without adequate intake of B12, vegans can easily develop deficiency over time, leading to symptoms such as fatigue, weakness, constipation, loss of appetite, weight loss, and nerve problems therefore the researchers recommend that vegans and vegetarians should add vitamin B12 to their diet by eating fermented foods, particular types of mushroom that contain the vitamin and B12-enriched vegetables

[30] For example, cyanocobalamin can be converted to its analog cobalamins via reduction to B 12s , followed by the addition of the corresponding alkyl halides, acyl halides, alkene or alkyne

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