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A large GWAS study that included 457,690 individuals (121,289 individuals with CAD and 63,495 individuals with myocardial infarction) showed that genetically determined elevated serum UA level was associated with the increased risk of CAD [OR =1.10 (95% CI: 1.061.15)] and myocardial infarction [OR =1.12 (95% CI: 1.071.18)]

We determined full-length high-resolution cryo electron microscopy (cryo-EM) structures of gB in its prefusion and postfusion conformation and describe the nanobody epitope and mode of neutralization

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