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The observed differences appear to be dependent on the animal model, as previous studies have shown that MitoQ is well tolerated at concentrations up to 500 M in drinking water over several weeks, without causing adverse effects on behavior or metabolism (57, 83)

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Pu Z, Han C, Zhang W, Xu M, Wu Z, Liu Y, Wu M, Sun H, Xie H (2019) Systematic understanding of the mechanism and effects of Arctigenin attenuates inflammation in dextran sulfate sodium-induced acute colitis through suppression of NLRP3 inflammasome by SIRT1

The role of HSP70 in cancer and its exploitation as a therapeutic target