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R-ALA is the preferred, natural form for better biological activity

While IGF-I remains the biomarker that best reflects endogenous GH secretion, when there is a discordancy with GH and IGF-I levels, it is important for the clinician to be mindful of the associated changes in intra-portal insulin delivery to the liver when interpreting these results in the context of health and when deciding treatment regimens in disease states

It is well documented that natural vitamin E is twice as effective as synthetics, since the former stays for longer in tissues [38]