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In these trials, PT-141 was generally well tolerated at single doses up to 1020 mg, with the main side effects being flushing and nausea (more on side effects later)

Exclusion criteria included non-English language studies, books, conference papers, case reports, in vitro studies, animal studies, and non-original articles

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One of those assigned to work on GLP-1 at Novo Nordisk was Lotte Bjerre Knudsen (figure 37), a young researcher hired by the company in 1989 straight after she completed her chemistry training at the Technical University of Denmark