Long-term augmentation therapy with alpha-1 antitrypsin in an MZ-AAT severe persistent asthma
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Co-treatment with a specific inhibitor of the lactate/H + transporter MCT1, AZD3965, led to increased apoptosis in APAP-treated cells, suggesting that lactate accumulation could be a cause of cell death in this model
For database search, oxidation of methionine and N -terminal acetylation, carbamidomethylation of cysteines, and artificial modification of amino acids cysteines (C), aspartic acids (D), glutamic acids (E), threonine (T), serine (S), tyrosines (Y), lysine K, or histidines (H) have been set as variable modifications