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Hereditary causes include genetic defects in the metabolism of amino acids, cholesterol, and fatty acids, such as propionyl-CoA carboxylase deficiency (aka propionic acidemia) and medium chain acyl-CoA dehydrogenase deficiency (36)

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In new data from ACHIEVE-2 and ACHIEVE-3, researchers compared efficacy of orforglipron in the type 2 diabetes populations with the SGLT2 inhibitor dapagliflozin (Farxiga, AstraZeneca) as well as the oral GLP-1 semaglutide (Ozempic pill, Novo Nordisk)

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