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Window 15 days What Was Measured Increased treadmill endurance at 25 mg/kg IP daily
Different sensitivity of chromatin to acid denaturation in quiescent and cycling cells as revealed by flow cytometry
In human studies, GLP-1 receptor agonists may slightly increase bone formation markers (eg, osteocalcin, bone alkaline phosphatase) and acutely reduce bone resorption markers, but these effects are modest and inconsistent
Patients who do not tolerate GLP-1 medications: those who had gastrointestinal side effects from semaglutide or tirzepatide and want to understand other options to discuss with a provider
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