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PMID: 15176951

Melasma, stretch marks, and hyperpigmentation that presented themselves in earlier trimesters are likely still lingering (theyll gradually start to fade, dont worry), and a few new concerns enter the chat, too

1,2 In 2021, an estimated 29.7 million adults in the United States (US) were diagnosed with diabetes, with an additional 8.7 to 9.8 million adults estimated to remain undiagnosed

The observed metabolic-research differences between the two compounds are therefore not explainable by tirzepatide hits GLP-1 harder. They are explainable by the synergistic effect of dual-receptor engagement, where GIPR activation amplifies the downstream consequence of a lower-affinity GLP-1R hit