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The pathogenesis of NDs, such as AD, PD, HD and ALS, is complex and multifactorial, involving oxidative stress, neuroinflammation, mitochondrial dysfunction and protein misfolding/aggregation

At the time, she shared that she was prescribed a medication for the condition but did not make any suggested diet or lifestyle changes, which she believes may have "very slowly made my condition worse." Mayim shared she was later diagnosed with connective tissue disease, mast cell activation syndrome (MCAS), Sjgren's syndrome and dysautonomia

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