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Some of the most common side effects include nausea, vomiting, diarrhea, bloating, and headache

Effect of tirzepatide on blood pressure and lipids: a meta-analysis of randomized controlled trials

and 148 were taking tirzepatide 15 mg

This change in food intake is largely mediated by estradiol, which acts directly upon anorexigenic and orexigenic neurons, largely in the hypothalamus