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The biologic significance of these data needs further examination, but these findings support our prior statements on the importance of immune cell phenotyping and the role of peripheral dopamine biomarkers in defining the mechanisms and/or prognosis of neuropsychiatric/neurodevelopmental disorders

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Thus, the use of extraphysiologic dopamine levels could produce confounding results by increasing the activation of receptors that may not be physiologically relevant and inducing aberrant effects due to cell death and the subsequent response to factors released from apoptotic cells

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