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Substance Use : Drugs like MDMA, alcohol, and some antidepressants affect serotonin production and reuptake, leading to long-term alterations in serotonin pathways

After 12 weeks, participants showed modest reductions in oxidative stress biomarkers (malondialdehyde, 8-OHdG) and slight improvements in fasting insulin levels, but no significant change in body weight or BMI

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